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Intestinal dysbiosis associated with systemic lupus erythematosus

Depending on stimuli, microglia can adopt distinct phenotypes: the M1 pro-inflammatory state (induced by lipopolysaccharide and characterized by production of cytokines such as TNF-, IL-1, and IL-6) and the M2 anti-inflammatory state (induced by IL-4 or IL-13, promoting repair) [122, 123]

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MiR-122 inhibition leads to decreased plasma cholesterol and triglyceride levels associated with altered lipids biosynthesis and increased FAO

10.1128/IAI.67.8.3824-3829.1999 150 VarmaS.GulatiK